Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics

Adolfo Ramirez-Zamora, James Giordano, Edward S. Boyden, Viviana Gradinaru, Aysegul Gunduz, Philip A. Starr, Sameer A. Sheth, Cameron C. McIntyre, Michael D. Fox, Jerrold Vitek, Vinata Vedam-Mai, Umer Akbar, Leonardo Almeida, Helen M. Bronte-Stewart, Helen S. Mayberg, Nader Pouratian, Aryn H. Gittis, Annabelle C. Singer, Meaghan C. Creed, Gabriel Lazaro-MunozMark Richardson, Marvin A. Rossi, Leopoldo Cendejas-Zaragoza, Pierre Francois D’Haese, Winston Chiong, Roee Gilron, Howard Chizeck, Andrew Ko, Kenneth B. Baker, Joost Wagenaar, Noam Harel, Wissam Deeb, Kelly D. Foote, Michael S. Okun

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The proceedings of the Sixth Annual Think Tank recapitulate progress in applications of neurotechnology, neurophysiology, and emerging techniques for the treatment of a range of psychiatric and neurological conditions including Parkinson’s disease, essential tremor, Tourette syndrome, epilepsy, cognitive disorders, and addiction. Each section of this overview provides insight about the understanding of neuromodulation for specific disease and discusses current challenges and future directions. This year’s report addresses key issues in implementing advanced neurophysiological techniques, evolving use of novel modulation techniques to deliver DBS, ans improved neuroimaging techniques. The proceedings also offer insights into the new era of brain network neuromodulation and connectomic DBS to define and target dysfunctional brain networks. The proceedings also focused on innovations in applications and understanding of adaptive DBS (closed-loop systems), the use and applications of optogenetics in the field of neurostimulation and the need to develop databases for DBS indications. Finally, updates on neuroethical, legal, social, and policy issues relevant to DBS research are discussed.

Original languageEnglish (US)
Article number936
JournalFrontiers in Neuroscience
StatePublished - Sep 12 2019
Externally publishedYes


  • Parkinson’s disease
  • Tourette syndrome
  • deep brain stimulation
  • epilepsy
  • neuromodulation
  • optogenetics
  • temporal dispersion
  • tremor

ASJC Scopus subject areas

  • Neuroscience(all)


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