@article{3b0939f6558b41b7a4e2c702f1470732,
title = "Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness",
abstract = "Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden for patients, families, and society worldwide. As part of the Curing Coma Campaign, the Neurocritical Care Society partnered with the National Institutes of Health to organize a symposium bringing together experts from all over the world to develop research targets for DoC. The conference was structured along six domains: (1) defining endotype/phenotypes, (2) biomarkers, (3) proof-of-concept clinical trials, (4) neuroprognostication, (5) long-term recovery, and (6) large datasets. This proceedings paper presents actionable research targets based on the presentations and discussions that occurred at the conference. We summarize the background, main research gaps, overall goals, the panel discussion of the approach, limitations and challenges, and deliverables that were identified.",
keywords = "Biomarkers, Coma, Consciousness, Electrophysiology, Magnetic resonance imaging",
author = "{the Curing Coma Campaign} and Jan Claassen and Yama Akbari and Sheila Alexander and Bader, {Mary Kay} and Kathleen Bell and Bleck, {Thomas P.} and Melanie Boly and Jeremy Brown and Chou, {Sherry H.Y.} and Diringer, {Michael N.} and Edlow, {Brian L.} and Brandon Foreman and Giacino, {Joseph T.} and Olivia Gosseries and Theresa Green and Greer, {David M.} and Hanley, {Daniel F.} and Hartings, {Jed A.} and Raimund Helbok and Hemphill, {J. Claude} and Hinson, {H. E.} and Karen Hirsch and Theresa Human and James, {Michael L.} and Nerissa Ko and Daniel Kondziella and Sarah Livesay and Madden, {Lori K.} and Shraddha Mainali and Mayer, {Stephan A.} and Victoria McCredie and McNett, {Molly M.} and Geert Meyfroidt and Monti, {Martin M.} and Susanne Muehlschlegel and Santosh Murthy and Paul Nyquist and Olson, {Dai Wai M.} and Provencio, {J. Javier} and Eric Rosenthal and {Sampaio Silva}, Gisele and Simone Sarasso and Schiff, {Nicholas D.} and Tarek Sharshar and Lori Shutter and Stevens, {Robert D.} and Paul Vespa and Walter Videtta and Amy Wagner and Wendy Ziai",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
month = jul,
doi = "10.1007/s12028-021-01260-x",
language = "English (US)",
volume = "35",
pages = "4--23",
journal = "Neurocritical Care",
issn = "1541-6933",
publisher = "Humana Press",
}