TY - JOUR
T1 - Probing the effects of phosphoinositides on ion channels.
AU - Huang, Chou Long
PY - 2006
Y1 - 2006
N2 - Ion channels are integral membrane proteins that control transmembrane ion fluxes to regulate membrane potential, cell excitability, and ion transport. Membrane phospholipids containing phosphoinositides have recently emerged as important regulators of many ion channels, including inward rectifier K+ channel, voltage-gated K+ and Ca2+ channels, transient receptor potential channels, and intracellular inositol-1,4,5-trisphosphate receptor ion channels. Discussed here are several methods for studying regulation of ion channels by phospholipids.
AB - Ion channels are integral membrane proteins that control transmembrane ion fluxes to regulate membrane potential, cell excitability, and ion transport. Membrane phospholipids containing phosphoinositides have recently emerged as important regulators of many ion channels, including inward rectifier K+ channel, voltage-gated K+ and Ca2+ channels, transient receptor potential channels, and intracellular inositol-1,4,5-trisphosphate receptor ion channels. Discussed here are several methods for studying regulation of ion channels by phospholipids.
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U2 - 10.1385/1-59745-095-2:81
DO - 10.1385/1-59745-095-2:81
M3 - Article
C2 - 16929940
AN - SCOPUS:36549041709
SN - 1064-3745
VL - 337
SP - 81
EP - 87
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -