TY - JOUR
T1 - Prized malaria drug target nailed
AU - Rathod, Pradipsinh K.
AU - Phillips, Margaret A.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - The structure of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase, a target of clinically established antimalarial drugs, reveals the nature of inhibitor binding, drug resistance and autologous gene repression, all of which influence species-specific drug sensitivity.
AB - The structure of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase, a target of clinically established antimalarial drugs, reveals the nature of inhibitor binding, drug resistance and autologous gene repression, all of which influence species-specific drug sensitivity.
UR - http://www.scopus.com/inward/record.url?scp=0037407201&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037407201&partnerID=8YFLogxK
U2 - 10.1038/nsb0503-316
DO - 10.1038/nsb0503-316
M3 - Short survey
C2 - 12714998
AN - SCOPUS:0037407201
SN - 1072-8368
VL - 10
SP - 316
EP - 318
JO - Nature Structural Biology
JF - Nature Structural Biology
IS - 5
ER -