TY - JOUR
T1 - Primary immune response of guinea pig spleen cells in vitro
AU - Kettman, J.
AU - Ben-Sasson, S.
AU - Rudin, J. U.
N1 - Funding Information:
* Supported by NIH Research Grants AI-11893, -11630 and -11851. ** Present address: Department of Immunology, Hadassa Medical School, Jerusalem, Israel. Abbreviations used: BSS = balanced salt solution; CRBC = chicken red blood cells; FCS = fetal calf serum; HRBC = horse red blood cells; NGPS = normal guinea pig serum; PEL --peritoneal exudate lymphocyte; PFC = plaque forming cells; SRBC = sheep red blood cells.
PY - 1978/4
Y1 - 1978/4
N2 - Spleen cells of the primed guinea pig, when cultured alone, failed to make a primary immune response against heterologous erythrocytes. When supplemented with lymphocytes obtained from mineral oil induced peritoneal exudate (PEL), a primary immune response against sheep, horse and chicken RBC was obtained. The kinetics, dose response and requirement of PELs for this response are reported.
AB - Spleen cells of the primed guinea pig, when cultured alone, failed to make a primary immune response against heterologous erythrocytes. When supplemented with lymphocytes obtained from mineral oil induced peritoneal exudate (PEL), a primary immune response against sheep, horse and chicken RBC was obtained. The kinetics, dose response and requirement of PELs for this response are reported.
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U2 - 10.1016/0022-1759(78)90251-X
DO - 10.1016/0022-1759(78)90251-X
M3 - Article
C2 - 77295
AN - SCOPUS:0017904382
SN - 0022-1759
VL - 20
SP - 131
EP - 141
JO - Journal of Immunological Methods
JF - Journal of Immunological Methods
IS - C
ER -