Prevention and treatment of nosocomial sepsis in the NICU

Reese Clark, Richard Powers, Robert White, Barry Bloom, Pablo Sanchez, Daniel K. Benjamin

Research output: Contribution to journalReview articlepeer-review

44 Scopus citations


Nosocomial sepsis a serious problem for neonates who are admitted for intensive care. It is associated with an increase in mortality, and prolonged lenght of hospital stay. Thus, both the human and fiscal costs of these infections are high. Although the rate of nosocomial sepsis increases with the degree of both prematurity and low birth weight, no specific lab test has been shown to be very useful in improving our ability to predict who has a "real" blood-steam infected and, therefore, who needs to be treated with a full course of antibiotics. As a result, antibiotic use is double the rate of "proven" sepsis and we are facilitating the growth of resistant organisms in the neonatal intensive care unit. The purpose of this article is to describe simple changes in process, which when implemented, can reduce nosocomial infection rates in neonates outcomes.

Original languageEnglish (US)
Pages (from-to)446-453
Number of pages8
JournalJournal of Perinatology
Issue number7
StatePublished - Jul 2004

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


Dive into the research topics of 'Prevention and treatment of nosocomial sepsis in the NICU'. Together they form a unique fingerprint.

Cite this