Presynaptic Unsilencing: Searching for a Mechanism

Deniz Atasoy, Ege T. Kavalali

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42.

Original languageEnglish (US)
Pages (from-to)345-346
Number of pages2
Issue number3
StatePublished - May 4 2006

ASJC Scopus subject areas

  • General Neuroscience


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