Prenatal diagnosis of the megacystis-megaureter association

J. Mandell, R. L. Lebowitz, Craig A Peters, J. A. Estroff, A. B. Retik, B. R. Benacerraf

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


A total of 11 male neonates with hydronephrosis and a large bladder in utero had the megacystis-megaureter association. Prenatal ultrasound findings included bilateral hydroureteronephrosis; a large, smooth, thin-walled bladder, and normal volume of amniotic fluid. Postnatal studies demonstrated grades 4 to 5 bilateral reflux, a large bladder without obstruction and in 2 infants nonfunction of a kidney or renal moiety. Of 7 infants initially managed nonoperatively 5 have undergone surgery due to persistent reflux or breakthrough urinary infections. The prenatal diagnosis of the megacystis- megaureter association can be suspected with reasonable accuracy. Prompt postnatal continuous antibiotic prophylaxis and uroradiological confirmation allow for nonemergency management of this condition with excellent results.

Original languageEnglish (US)
Pages (from-to)1487-1489
Number of pages3
JournalJournal of Urology
Issue number5 I
StatePublished - 1992


  • abnormalities
  • bladder
  • prenatal diagnosis
  • ultrasonic diagnosis
  • ureter

ASJC Scopus subject areas

  • Urology


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