Abstract
The activity of potassium channels of canine aortic sarcoplasmic reticulum was measured using the planar lipid bilayer-fusion technique. The channels have a conductance of 208 pS ( 400 100 mM K+ in cis/trans solutions) and potassium-to-sodium permeability ratio of 7.7. Ba2+ ions produced two main effects: one is the interruption of channel currents for tens to hundreds of milliseconds in a voltage-dependent manner, and the other is the appearance of a second conductance level with amplitude about 60% of the main level.
Original language | English (US) |
---|---|
Pages (from-to) | 75-80 |
Number of pages | 6 |
Journal | BBA - Biomembranes |
Volume | 1064 |
Issue number | 1 |
DOIs | |
State | Published - Apr 26 1991 |
Keywords
- (Canine aorta)
- Barium ion blockage
- Bilayer
- Conductance level
- Microsome
- Potassium ion channel
- Sarcoplasmic reticulum
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Cell Biology