TY - JOUR
T1 - Posttraumatic Stress Disorder After Spontaneous Coronary Artery Dissection
T2 - A Report of the International Spontaneous Coronary Artery Dissection Registry
AU - Sumner, Jennifer A.
AU - Kim, Esther S.H.
AU - Wood, Malissa J.
AU - Chi, Gerald
AU - Nolen, Jessica
AU - Grodzinsky, Anna
AU - Gornik, Heather L.
AU - Kadian-Dodov, Daniella
AU - Wells, Bryan J.
AU - Hess, Connie N.
AU - Lewey, Jennifer
AU - Tam, Lori
AU - Henkin, Stanislav
AU - Orford, James
AU - Wells, Gretchen
AU - Kumbhani, Dharam J.
AU - Lindley, Kathryn J.
AU - Gibson, C. Michael
AU - Leon, Katherine K.
AU - Naderi, Sahar
PY - 2024/4/2
Y1 - 2024/4/2
N2 - BACKGROUND: Myocardial infarction secondary to spontaneous coronary artery dissection (SCAD) can be traumatic and potentially trigger posttraumatic stress disorder (PTSD). In a large, multicenter, registry-based cohort, we documented prevalence of lifetime and past-month SCAD-induced PTSD, as well as related treatment seeking, and examined a range of health-relevant correlates of SCAD-induced PTSD. METHODS AND RESULTS: Patients with SCAD were enrolled in the iSCAD (International SCAD) Registry. At baseline, site investigators completed medical report forms, and patients reported demographics, medical/SCAD history, psychosocial factors (including SCAD-induced PTSD symptoms), health behaviors, and health status via online questionnaires. Of 1156 registry patients, 859 patients (93.9% women; mean age, 52.3 years) completed questionnaires querying SCAD-induced PTSD. Nearly 35% (n=298) of patients met diagnostic criteria for probable SCAD-induced PTSD in their lifetime, and 6.4% (n=55) met criteria for probable past-month PTSD. Of 811 patients ever reporting any SCAD-induced PTSD symptoms, 34.8% indicated seeking treatment for this distress. However, 46.0% of the 298 patients with lifetime probable SCAD-induced PTSD diagnoses reported never receiving trauma-related treatment. Younger age at first SCAD, fewer years since SCAD, being single, unemployed status, more lifetime trauma, and history of anxiety were associated with greater past-month PTSD symptom severity in multivariable regression models. Greater past-month SCAD-induced PTSD symptoms were associated with greater past-week sleep disturbance and worse past-month disease-specific health status when adjusting for various risk factors. CONCLUSIONS: Given the high prevalence of SCAD-induced PTSD symptoms, efforts to support screening for these symptoms and connecting patients experiencing distress with empirically supported treatments are critical next steps. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04496687.
AB - BACKGROUND: Myocardial infarction secondary to spontaneous coronary artery dissection (SCAD) can be traumatic and potentially trigger posttraumatic stress disorder (PTSD). In a large, multicenter, registry-based cohort, we documented prevalence of lifetime and past-month SCAD-induced PTSD, as well as related treatment seeking, and examined a range of health-relevant correlates of SCAD-induced PTSD. METHODS AND RESULTS: Patients with SCAD were enrolled in the iSCAD (International SCAD) Registry. At baseline, site investigators completed medical report forms, and patients reported demographics, medical/SCAD history, psychosocial factors (including SCAD-induced PTSD symptoms), health behaviors, and health status via online questionnaires. Of 1156 registry patients, 859 patients (93.9% women; mean age, 52.3 years) completed questionnaires querying SCAD-induced PTSD. Nearly 35% (n=298) of patients met diagnostic criteria for probable SCAD-induced PTSD in their lifetime, and 6.4% (n=55) met criteria for probable past-month PTSD. Of 811 patients ever reporting any SCAD-induced PTSD symptoms, 34.8% indicated seeking treatment for this distress. However, 46.0% of the 298 patients with lifetime probable SCAD-induced PTSD diagnoses reported never receiving trauma-related treatment. Younger age at first SCAD, fewer years since SCAD, being single, unemployed status, more lifetime trauma, and history of anxiety were associated with greater past-month PTSD symptom severity in multivariable regression models. Greater past-month SCAD-induced PTSD symptoms were associated with greater past-week sleep disturbance and worse past-month disease-specific health status when adjusting for various risk factors. CONCLUSIONS: Given the high prevalence of SCAD-induced PTSD symptoms, efforts to support screening for these symptoms and connecting patients experiencing distress with empirically supported treatments are critical next steps. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04496687.
KW - PTSD
KW - SCAD
KW - health status
KW - sleep
KW - trauma
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=85189750276&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85189750276&partnerID=8YFLogxK
U2 - 10.1161/JAHA.123.032819
DO - 10.1161/JAHA.123.032819
M3 - Article
C2 - 38533943
AN - SCOPUS:85189750276
SN - 2047-9980
VL - 13
SP - e032819
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 7
ER -