@inproceedings{dd71b107db94455faa2efb51b15d359f,
title = "Porcine skin ED50 damage thresholds for 1214 nm laser irradiation",
abstract = "A series of experiments were conducted in vivo on porcine skin to determine the ED50 damage thresholds for 1214 nm continuous wave laser irradiation. These results provide new information for refinement of Maximum Permissible Exposure (MPE). The study employed exposure durations of 1 sec, 3 sec, and 10 seconds with nominal spot diameters of 6 mm, 8 mm and 10 mm and as a function of laser power. The effect of each irradiation was evaluated acutely, one hour after exposure, and 24 hours post exposure. Probit analysis was conducted to estimate the dose for 50% probability of laser-induced damage (ED50); Damage was defined as persistent redness at the site of irradiation for the pig skin after 24 hours. The results indicated that Maximum Permissible Exposure (MPE) limits should be lowered for the laser beam diameters larger than 6 mm.",
author = "Bo Chen and Jeffrey Oliver and Rebecca Vincelette and Ginger Pocock and Raiyan Zaman and Welch, {Ashley J.}",
year = "2008",
doi = "10.1117/12.761380",
language = "English (US)",
isbn = "9780819470294",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Optical Interactions with Tissue and Cells XIX",
note = "Optical Interactions with Tissue and Cells XIX ; Conference date: 21-01-2008 Through 23-01-2008",
}