Plug-and-Play Shape Refinement Framework for Multi-site and Lifespan Brain Skull Stripping

Yunxiang Li, Ruilong Dan, Shuai Wang, Yifan Cao, Xiangde Luo, Chenghao Tan, Gangyong Jia, Huiyu Zhou, You Zhang, Yaqi Wang, Li Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Skull stripping is a crucial prerequisite step in the analysis of brain magnetic resonance images (MRI). Although many excellent works or tools have been proposed, they suffer from low generalization capability. For instance, the model trained on a dataset with specific imaging parameters cannot be well applied to other datasets with different imaging parameters. Especially, for the lifespan datasets, the model trained on an adult dataset is not applicable to an infant dataset due to the large domain difference. To address this issue, numerous methods have been proposed, where domain adaptation based on feature alignment is the most common. Unfortunately, this method has some inherent shortcomings, which need to be retrained for each new domain and requires concurrent access to the input images of both domains. In this paper, we design a plug-and-play shape refinement (PSR) framework for multi-site and lifespan skull stripping. To deal with the domain shift between multi-site lifespan datasets, we take advantage of the brain shape prior, which is invariant to imaging parameters and ages. Experiments demonstrate that our framework can outperform the state-of-the-art methods on multi-site lifespan datasets.

Original languageEnglish (US)
Title of host publicationMachine Learning in Medical Imaging - 13th International Workshop, MLMI 2022, Held in Conjunction with MICCAI 2022, Proceedings
EditorsChunfeng Lian, Xiaohuan Cao, Islem Rekik, Xuanang Xu, Zhiming Cui
PublisherSpringer Science and Business Media Deutschland GmbH
Pages81-90
Number of pages10
ISBN (Print)9783031210136
DOIs
StatePublished - 2022
Event13th International Workshop on Machine Learning in Medical Imaging, MLMI 2022, held in conjunction with 25th International Conference on Medical Image Computing and Computer_Assisted Intervention, MICCAI 2022 - Singapore, Singapore
Duration: Sep 18 2022Sep 18 2022

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume13583 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference13th International Workshop on Machine Learning in Medical Imaging, MLMI 2022, held in conjunction with 25th International Conference on Medical Image Computing and Computer_Assisted Intervention, MICCAI 2022
Country/TerritorySingapore
CitySingapore
Period9/18/229/18/22

Keywords

  • Domain adaptation
  • Lifespan brain
  • Shape dictionary
  • Skull stripping
  • Transformer

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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