Plasma Glucagon in Nonketotic Hyperosmolar Coma

C. A. Lindsey; G. R. Faloona; Roger H Unger

doi:10.1001/jama.1974.03230510045021

Plasma Glucagon in Nonketotic Hyperosmolar Coma

C. A. Lindsey, G. R. Faloona, Roger H Unger

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Abstract

To determine if hyperglucagonemia is present in the nonketotic hyperglycemic hyperosmolar syndrome as it is in diabetic ketoacidosis, we measured plasma glucagon in seven patients hospitalized with the former diagnosis. Despite blood glucose levels ranging from 812 to 1,224 mg/100 ml, plasma glucagon averaged 689 pg/ml (SEM±215), and ranged from 130 to 1,825 pg/ml. Hyperglucagonemia is a common finding in this form of poorly controlled diabetes.

Original language	English (US)
Pages (from-to)	1771-1773
Number of pages	3
Journal	JAMA: The Journal of the American Medical Association
Volume	229
Issue number	13
DOIs	https://doi.org/10.1001/jama.1974.03230510045021
State	Published - Sep 23 1974

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Medicine(all)

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10.1001/jama.1974.03230510045021

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AB - To determine if hyperglucagonemia is present in the nonketotic hyperglycemic hyperosmolar syndrome as it is in diabetic ketoacidosis, we measured plasma glucagon in seven patients hospitalized with the former diagnosis. Despite blood glucose levels ranging from 812 to 1,224 mg/100 ml, plasma glucagon averaged 689 pg/ml (SEM±215), and ranged from 130 to 1,825 pg/ml. Hyperglucagonemia is a common finding in this form of poorly controlled diabetes.

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Plasma Glucagon in Nonketotic Hyperosmolar Coma

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