Physical Activity Reduces the Risk of Recurrence and Mortality in Cancer Patients

Justin C. Brown; L. Anne Gilmore

doi:10.1249/JES.0000000000000214

Physical Activity Reduces the Risk of Recurrence and Mortality in Cancer Patients

Justin C. Brown, L. Anne Gilmore

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

The biological mechanisms through which physical activity reduces metastatic disease recurrence and mortality in cancer patients are not known. This review offers the hypothesis that physical activity reduces the risk of recurrence and mortality in cancer patients through two synergistic processes: 1) indirect (systemic) effects related to the host tumor microenvironment; and 2) direct (physical) effects on cancer cells.

Original language	English (US)
Pages (from-to)	67-73
Number of pages	7
Journal	Exercise and Sport Sciences Reviews
Volume	48
Issue number	2
DOIs	https://doi.org/10.1249/JES.0000000000000214
State	Published - Apr 1 2020
Externally published	Yes

Keywords

disease progression
exercise
microfluidics
neoplastic cells
prognosis
tumor microenvironment

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1249/JES.0000000000000214

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title = "Physical Activity Reduces the Risk of Recurrence and Mortality in Cancer Patients",

abstract = "The biological mechanisms through which physical activity reduces metastatic disease recurrence and mortality in cancer patients are not known. This review offers the hypothesis that physical activity reduces the risk of recurrence and mortality in cancer patients through two synergistic processes: 1) indirect (systemic) effects related to the host tumor microenvironment; and 2) direct (physical) effects on cancer cells.",

keywords = "disease progression, exercise, microfluidics, neoplastic cells, prognosis, tumor microenvironment",

author = "Brown, {Justin C.} and Gilmore, {L. Anne}",

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AU - Gilmore, L. Anne

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PY - 2020/4/1

Y1 - 2020/4/1

N2 - The biological mechanisms through which physical activity reduces metastatic disease recurrence and mortality in cancer patients are not known. This review offers the hypothesis that physical activity reduces the risk of recurrence and mortality in cancer patients through two synergistic processes: 1) indirect (systemic) effects related to the host tumor microenvironment; and 2) direct (physical) effects on cancer cells.

AB - The biological mechanisms through which physical activity reduces metastatic disease recurrence and mortality in cancer patients are not known. This review offers the hypothesis that physical activity reduces the risk of recurrence and mortality in cancer patients through two synergistic processes: 1) indirect (systemic) effects related to the host tumor microenvironment; and 2) direct (physical) effects on cancer cells.

KW - disease progression

KW - exercise

KW - microfluidics

KW - neoplastic cells

KW - prognosis

KW - tumor microenvironment

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Physical Activity Reduces the Risk of Recurrence and Mortality in Cancer Patients

Abstract

Keywords

ASJC Scopus subject areas

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