TY - JOUR
T1 - Phase separation of BuGZ promotes Aurora A activation and spindle assembly
AU - Woodruff, Jeffrey B.
N1 - Funding Information:
J.B. Woodruff was supported by funding from the Max Planck Research Network in Synthetic Biology. The author declares no competing financial interests.
Publisher Copyright:
© 2018 Woodruff.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - The spindle matrix has been proposed to facilitate mitotic spindle assembly. In this issue, Huang et al. (2018. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201706103) show that the spindle matrix protein BuGZ is sufficient to form micron-scale compartments that recruit and activate Aurora A, a critical kinase for spindle assembly.
AB - The spindle matrix has been proposed to facilitate mitotic spindle assembly. In this issue, Huang et al. (2018. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201706103) show that the spindle matrix protein BuGZ is sufficient to form micron-scale compartments that recruit and activate Aurora A, a critical kinase for spindle assembly.
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U2 - 10.1083/jcb.201711070
DO - 10.1083/jcb.201711070
M3 - Comment/debate
C2 - 29263080
AN - SCOPUS:85039851482
SN - 0021-9525
VL - 217
SP - 9
EP - 10
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 1
ER -