Pharmacologic optimization of microsurgery in the new millennium

M. H. Conrad, Jr Adams

Research output: Contribution to journalReview articlepeer-review

93 Scopus citations


Microsurgical anastomoses are largely technically dependent; however, there exists a finite rate of failure, with often devastating consequences. Pharmacologic prophylaxis and intervention are used extensively in microsurgical cases, yet a unified algorithm does not exist among the various basic science and clinical studies in the literature. This results in a confusing and nonstandardized practice based on anecdotal experiences. The purpose of this article is to review the literature on this topic and synthesize a practical clinical management algorithm for pharmacologic therapy in microsurgery.

Original languageEnglish (US)
Pages (from-to)2088-2096
Number of pages9
JournalPlastic and reconstructive surgery
Issue number7
StatePublished - 2001

ASJC Scopus subject areas

  • Surgery


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