Persistent fetal vasculature presenting with axial elongation and platyphakia

James Lin, Manuel Paez-Escamilla, Laila E. Teira, Brenda Fallas, J. William Harbour

Research output: Contribution to journalArticlepeer-review


Leukocoria in children should always raise the concern for retinoblastoma. However, a variety of non-neoplastic conditions can also present with leukocoria, including persistent fetal vasculature (PFV), a nonhereditary, congenital anomaly caused by a failure of the fetal intraocular vasculature to regress during development. Classically PFV presents with features that make it easily distinguishable from retinoblastoma, including microphthalmia, retrolental fibrovascular membrane, central dragging of ciliary processes, and cataract. We present an atypical case of PFV in a 9-month-old boy who presented with the unusual features of axial myopia and platyphakia.

Original languageEnglish (US)
Pages (from-to)51-53
Number of pages3
JournalJournal of AAPOS
Issue number1
StatePublished - Feb 2019
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology


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