Persistence of alphaviruses in vertebrate hosts

Beth Levine, J. Marie Hardwick, Diane E. Griffin

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


Alphaviruses are a group of arthropod-borne, positive-strand RNA viruses that cause acute encephalitis or arthritis. These viruses were previously thought to cause only acute infections in vertebrates, but recent evidence suggests that host immunological and tissue-specific factors may act together to promote the persistence of alphavirus genomes in vivo.

Original languageEnglish (US)
Pages (from-to)25-28
Number of pages4
JournalTrends in Microbiology
Issue number1
StatePublished - Jan 1994

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


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