Penile transplantation: an emerging option for genitourinary reconstruction

Sami H. Tuffaha, Damon S. Cooney, Nikolai A. Sopko, Trinity J. Bivalacqua, Denver M. Lough, Carisa M. Cooney, Gerald Brandacher, Wei Ping Andrew Lee, Arthur L. Burnett, Richard J. Redett

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.

Original languageEnglish (US)
Pages (from-to)441-450
Number of pages10
JournalTransplant International
Issue number5
StatePublished - May 2017
Externally publishedYes


  • penile defects
  • penile transplant
  • reconstructive surgical procedures
  • vascularized composite allotransplantation

ASJC Scopus subject areas

  • Transplantation


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