TY - JOUR
T1 - Pediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline
T2 - Report of the AAN Guidelines Subcommittee, AAP, CNS, and SCCM
AU - Greer, David M.
AU - Kirschen, Matthew P.
AU - Lewis, Ariane
AU - Gronseth, Gary S.
AU - Rae-Grant, Alexander
AU - Ashwal, Stephen
AU - Babu, Maya A.
AU - Bauer, David F.
AU - Billinghurst, Lori
AU - Corey, Amanda
AU - Partap, Sonia
AU - Rubin, Michael A.
AU - Shutter, Lori
AU - Takahashi, Courtney
AU - Tasker, Robert C.
AU - Varelas, Panayiotis Nicolaou
AU - Wijdicks, Eelco
AU - Bennett, Amy
AU - Wessels, Scott R.
AU - Halperin, John J.
N1 - Publisher Copyright:
© American Academy of Neurology.
PY - 2023/12/12
Y1 - 2023/12/12
N2 - Background and ObjectivesThe purpose of this guideline is to update the 2010 American Academy of Neurology (AAN) brain death/death by neurologic criteria (BD/DNC) guideline for adults and the 2011 American Academy of Pediatrics, Child Neurology Society, and Society of Critical Care Medicine guideline for infants and children and to clarify the BD/DNC determination process by integrating guidance for adults and children into a single guideline. Updates in this guideline include guidance related to conducting the BD/DNC evaluation in the context of extracorporeal membrane oxygenation, targeted temperature management, and primary infratentorial injury.MethodsA panel of experts from multiple medical societies developed BD/DNC recommendations. Because of the lack of high-quality evidence on the subject, a novel, evidence-informed formal consensus process was used. This process relied on the panel experts' review and detailed knowledge of the literature surrounding BD/DNC to guide the development of preliminary recommendations. Recommendations were formulated and voted on, using a modified Delphi process, according to the 2017 AAN Clinical Practice Guideline Process Manual.Major RecommendationsEighty-five recommendations were developed on the following: (1) general principles for the BD/DNC evaluation, (2) qualifications to perform BD/DNC evaluations, (3) prerequisites for BD/DNC determination, (4) components of the BD/DNC neurologic examination, (5) apnea testing as part of the BD/DNC evaluation, (6) ancillary testing as part of the BD/DNC evaluation, and (7) special considerations for BD/DNC determination.
AB - Background and ObjectivesThe purpose of this guideline is to update the 2010 American Academy of Neurology (AAN) brain death/death by neurologic criteria (BD/DNC) guideline for adults and the 2011 American Academy of Pediatrics, Child Neurology Society, and Society of Critical Care Medicine guideline for infants and children and to clarify the BD/DNC determination process by integrating guidance for adults and children into a single guideline. Updates in this guideline include guidance related to conducting the BD/DNC evaluation in the context of extracorporeal membrane oxygenation, targeted temperature management, and primary infratentorial injury.MethodsA panel of experts from multiple medical societies developed BD/DNC recommendations. Because of the lack of high-quality evidence on the subject, a novel, evidence-informed formal consensus process was used. This process relied on the panel experts' review and detailed knowledge of the literature surrounding BD/DNC to guide the development of preliminary recommendations. Recommendations were formulated and voted on, using a modified Delphi process, according to the 2017 AAN Clinical Practice Guideline Process Manual.Major RecommendationsEighty-five recommendations were developed on the following: (1) general principles for the BD/DNC evaluation, (2) qualifications to perform BD/DNC evaluations, (3) prerequisites for BD/DNC determination, (4) components of the BD/DNC neurologic examination, (5) apnea testing as part of the BD/DNC evaluation, (6) ancillary testing as part of the BD/DNC evaluation, and (7) special considerations for BD/DNC determination.
UR - http://www.scopus.com/inward/record.url?scp=85179947161&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85179947161&partnerID=8YFLogxK
U2 - 10.1212/WNL.0000000000207740
DO - 10.1212/WNL.0000000000207740
M3 - Article
C2 - 37821233
AN - SCOPUS:85179947161
SN - 0028-3878
VL - 101
SP - 1112
EP - 1132
JO - Neurology
JF - Neurology
IS - 24
ER -