@inproceedings{9879219bdbdd4252b3b110b32ce36ab3,
title = "Patterned nanomagnets on-chip for screening circulating tumor cells in blood",
abstract = "Circulating tumor cells (CTCs) are considered potential indicators for prognosis and clinical management. However, detection of CTCs is very challenging due to its rarity (the ratio per CTC to leukocyte is 1:10 7-109). 0We have previously developed a microchip-based immunomagnetic screening system for the isolation of CTCs from whole blood samples. The system has been successfully applied in cancer patient sample screening. Here, we report arrays of directly patterned metallic nanomagnets on a channel substrate that locally enhance magnetic field and further improve system's capture capability. The proposed screening system can be a powerful platform for the cancer management.",
keywords = "Circulating tumor cell, Immunomagnetic, Microchip, Nanomagnets",
author = "Huang, {Yu Yen} and Peng Chen and Kazunori Hoshino and Wu, {Chun Hsien} and Nancy Lane and Michael Huebschman and Jonathan Uhr and Konstantin Sokolov and Eugene Frenkel and Xiaojing Zhang",
year = "2012",
month = jan,
day = "1",
language = "English (US)",
isbn = "9780979806452",
series = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
publisher = "Chemical and Biological Microsystems Society",
pages = "1117--1119",
booktitle = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
note = "16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 ; Conference date: 28-10-2012 Through 01-11-2012",
}