Patient and provider perspectives on delivery of oral cancer therapies

Caitlin C. Murphy, Simon J.Craddock Lee, David E. Gerber, John V. Cox, Hannah M. Fullington, Robin T. Higashi

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Objective: The introduction of oral cancer therapies presents new challenges to delivery of quality cancer care. Little is known about how patients and providers address and overcome these challenges. We conducted a qualitative study exploring the range of patient and provider perspectives on oral cancer therapies. Methods: We conducted semi-structured interviews with patients and providers at a tertiary referral center and county safety-net hospital in Dallas, TX. Interviews probed perspectives on differences between parenteral chemotherapy and oral therapies, adherence, communication, and cost/insurance. Interview transcripts were analyzed thematically using a deductively-driven coding scheme corresponding to the interview guide. Results: We conducted 22 patient (13 at tertiary referral center, 9 at safety-net hospital) and 10 provider (7 oncologists, 2 nurses, 1 pharmacist) interviews. Key themes from interviews included: (1) differences in parenteral chemotherapy vs. oral therapy; (2) adherence and dosing; and (3) experiences related to cost and communication. Conclusions: Nearly all providers described challenges engaging with and educating patients about oral cancer therapies. Despite our initial hypothesis, safety-net patients encountered few barriers accessing oral therapies compared to patients receiving care in the tertiary referral center. Practice implications: : Our findings will guide future interventions to monitor and support cancer patients receiving oral therapies.

Original languageEnglish (US)
Pages (from-to)2102-2109
Number of pages8
JournalPatient Education and Counseling
Issue number11
StatePublished - Nov 2019


  • Cancer
  • Health disparities
  • Medication adherence
  • Qualitative research

ASJC Scopus subject areas

  • Medicine(all)


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