Pathophysiology and Management of Calcium Stones

Sangtae Park, Margaret S Pearle

Research output: Contribution to journalReview articlepeer-review

83 Scopus citations


Nephrolithiasis is a common disorder that accounts for significant cost, morbidity, and loss of work. There is a one in eight lifetime chance of being diagnosed with urinary stones. Calcium is the most common component of renal stones in individuals in industrialized nations. Calcium stones form as a result of a variety of environmental and metabolic abnormalities that change the urinary environment and increase supersaturation of stone-forming salts. Understanding the pathophysiology of stone disease can help direct treatment toward correction of the underlying abnormalities. Current medical and dietary therapeutic regimens have been shown to significantly reduce the risk of recurrent stone formation.

Original languageEnglish (US)
Pages (from-to)323-334
Number of pages12
JournalUrologic Clinics of North America
Issue number3
StatePublished - Aug 2007

ASJC Scopus subject areas

  • Urology


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