Paraneoplastic diarrhea in a patient with lung adenocarcinoma

Anh D. Nguyen; Mark A. Valasek; Ezra Burstein

doi:10.1007/s12328-013-0407-9

Paraneoplastic diarrhea in a patient with lung adenocarcinoma

Anh D. Nguyen, Mark A. Valasek, Ezra Burstein

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We present a case of newly diagnosed lung adenocarcinoma and a five-month history of diarrhea. The patient was found to have elevated chromogranin A serum levels and the tumor displayed histologic and immunohistochemical features of neuroendocrine differentiation. Upon lobectomy and tumor resection, the chromogranin A levels normalized and the diarrhea resolved completely. This is the first reported case of paraneoplastic diarrhea associated with lung adenocarcinoma.

Original language	English (US)
Pages (from-to)	357-360
Number of pages	4
Journal	Clinical Journal of Gastroenterology
Volume	6
Issue number	5
DOIs	https://doi.org/10.1007/s12328-013-0407-9
State	Published - Oct 2013

Keywords

Lung cancer
Paraneoplastic
Secretory diarrhea

ASJC Scopus subject areas

Gastroenterology

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10.1007/s12328-013-0407-9

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title = "Paraneoplastic diarrhea in a patient with lung adenocarcinoma",

abstract = "We present a case of newly diagnosed lung adenocarcinoma and a five-month history of diarrhea. The patient was found to have elevated chromogranin A serum levels and the tumor displayed histologic and immunohistochemical features of neuroendocrine differentiation. Upon lobectomy and tumor resection, the chromogranin A levels normalized and the diarrhea resolved completely. This is the first reported case of paraneoplastic diarrhea associated with lung adenocarcinoma.",

keywords = "Lung cancer, Paraneoplastic, Secretory diarrhea",

author = "Nguyen, {Anh D.} and Valasek, {Mark A.} and Ezra Burstein",

note = "Funding Information: Conflict of interest The authors declare no financial, professional, or personal conflict of interest. EB is supported by an NIH R01 Grant (DK073639) and a CCFA award (SRA # 2373). For the remaining authors none were declared.",

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T1 - Paraneoplastic diarrhea in a patient with lung adenocarcinoma

AU - Nguyen, Anh D.

AU - Valasek, Mark A.

AU - Burstein, Ezra

N1 - Funding Information: Conflict of interest The authors declare no financial, professional, or personal conflict of interest. EB is supported by an NIH R01 Grant (DK073639) and a CCFA award (SRA # 2373). For the remaining authors none were declared.

PY - 2013/10

Y1 - 2013/10

N2 - We present a case of newly diagnosed lung adenocarcinoma and a five-month history of diarrhea. The patient was found to have elevated chromogranin A serum levels and the tumor displayed histologic and immunohistochemical features of neuroendocrine differentiation. Upon lobectomy and tumor resection, the chromogranin A levels normalized and the diarrhea resolved completely. This is the first reported case of paraneoplastic diarrhea associated with lung adenocarcinoma.

AB - We present a case of newly diagnosed lung adenocarcinoma and a five-month history of diarrhea. The patient was found to have elevated chromogranin A serum levels and the tumor displayed histologic and immunohistochemical features of neuroendocrine differentiation. Upon lobectomy and tumor resection, the chromogranin A levels normalized and the diarrhea resolved completely. This is the first reported case of paraneoplastic diarrhea associated with lung adenocarcinoma.

KW - Lung cancer

KW - Paraneoplastic

KW - Secretory diarrhea

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JF - Clinical Journal of Gastroenterology

IS - 5

ER -

Paraneoplastic diarrhea in a patient with lung adenocarcinoma

Abstract

Keywords

ASJC Scopus subject areas

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