Parallel imaging enhanced MR colonography using a phantom model

Martina M. Morrin, Ivan Pedrosa, Charles A. McKenzie, Richard J. Farrell, Nicolas Bloch, Stephanie Solazzo, Long Ngo, Shraga N. Goldberg, Neil M. Rofsky

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Purpose: To compare various Array Spatial and Sensitivity Encoding Technique (ASSET)-enhanced T2W SSFSE (single shot fast spin echo) and T1-weighted (T1W) 3D SPGR (spoiled gradient recalled echo) sequences for polyp detection and image quality at MR colonography (MRC) in a phantom model. Limitations of MRC using standard 3D SPGR T1W imaging include the long breath-hold required to cover the entire colon within one acquisition and the relatively low spatial resolution due to the long acquisition time. Parallel imaging using ASSET-enhanced T2W SSFSE and 3D T1W SPGR imaging results in much shorter imaging times, which allows for increased spatial resolution. Materials and Methods: Using two porcine colon phantoms each with eight simulated 3-10-mm "polyps," baseline reference sequences acquired without ASSET (6-mm slices and readout bandwidth [BW] 62 kHz) were compared with 11 SSFSE and 8 SPGR sequences acquired with 2-fold ASSET acceleration. ASSET-enhanced SSFSE and SPGR sequences comprised BW/matrix combinations ranging from 20-62 kHz / 256-352 x 256, respectively, with slice thicknesses adjusted from 3.0 to 4.5 mm to maintain a 23-26-second acquisition time and 30 cm slab thickness. Two experienced radiologists viewed the datasets in a randomized, blinded fashion. Results: Compared to reference sequences, ASSET-enhanced SSFSE and SPGR sequences facilitated better polyp detection and had similar overall image quality and perphantom specificity. The two best ASSET-enhanced SSFSE (3 and 4.5 mm slices, each with BW of 62.5 kHz and 352 x 256 matrices) and three best ASSET-enhanced SPGR BW / slice thickness / matrix combinations of 31 kHz / 4.4 msec / 192 X 256; 62 / 3.4 / 192 X 256; and 62 / 4.0 / 192 X 256, respectively, permitted detection of all polyps ≥ 5 mm. Conclusion: Parallel imaging using ASSET-enhanced T2W SSFSE and T1W 3D SPGR improves the ability to detect significant colon polyps in an MRC phantom model.

Original languageEnglish (US)
Pages (from-to)664-672
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Issue number3
StatePublished - Sep 2008


  • Colon phantom
  • MR colonography
  • Parallel imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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