Pan American League of Associations for Rheumatology recommendations for the management of axial spondyloarthritis

Wilson Bautista-Molano, Daniel G. Fernández-Ávila, María Lorena Brance, María Gabriela Ávila Pedretti, Ruben Burgos-Vargas, Inés Corbacho, Vanesa Laura Cosentino, José Francisco Díaz Coto, Enrique Giraldo Ho, Gustavo Gomes Resende, Luis Arturo Gutiérrez, Marwin Gutiérrez, Sebastián Eduardo Ibáñez Vodnizza, Edwin Jáuregui, Vanessa Ocampo, Daniel Ruben Palleiro Rivero, Penélope Esther Palominos, Cesar Pacheco Tena, Guillermo Andrés Quiceno, Lina María Saldarriaga-RiveraFernando Andrés Sommerfleck, Annelise Goecke Sariego, Claudia Vera Barrezueta, Luis Enrique Vega Espinoza, Oscar Vega Hinojosa, Gustavo Citera, Carlos Lozada, Percival D. Sampaio-Barros, Emilce Schneeberger, Enrique R. Soriano

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Axial spondyloarthritis (axSpA) comprises a spectrum of chronic inflammatory manifestations affecting the axial skeleton and represents a challenge for diagnosis and treatment. Our objective was to generate a set of evidence-based recommendations for the management of axSpA for physicians, health professionals, rheumatologists and policy decision makers in Pan American League of Associations for Rheumatology (PANLAR) countries. Grading of Recommendations, Assessment, Development and Evaluation-ADOLOPMENT methodology was used to adapt existing recommendations after performing an independent systematic search and synthesis of the literature to update the evidence. A working group consisting of rheumatologists, epidemiologists and patient representatives from countries within the Americas prioritized 13 topics relevant to the context of these countries for the management of axSpA. This Evidence-Based Guideline article reports 13 recommendations addressing therapeutic targets, the use of NSAIDs and glucocorticoids, treatment with DMARDs (including conventional synthetic, biologic and targeted synthetic DMARDs), therapeutic failure, optimization of the use of biologic DMARDs, the use of drugs for extra-musculoskeletal manifestations of axSpA, non-pharmacological interventions and the follow-up of patients with axSpA.

Original languageEnglish (US)
Pages (from-to)724-737
Number of pages14
JournalNature Reviews Rheumatology
Volume19
Issue number11
DOIs
StatePublished - Nov 2023
Externally publishedYes

ASJC Scopus subject areas

  • Rheumatology

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