TY - JOUR
T1 - Pain management of acute limb trauma patients with intravenous lidocaine in emergency department
AU - Farahmand, Shervin
AU - Hamrah, Hadid
AU - Arbab, Mona
AU - Sedaghat, Mojtaba
AU - Basir Ghafouri, Hamed
AU - Bagheri-Hariri, Shahram
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2018/7
Y1 - 2018/7
N2 - Introduction: This study was designed to assess the possible superiority of intravenous lidocaine to morphine for pain management. Methods: This was a randomized double blind controlled superiority trial, carried on in the emergency department (ED). Traumatic patients older than 18-year-old with the complaint of acute pain greater than 4 on a numeric rating scale (NRS) from 0 to 10 on their extremities were eligible. One group received IV lidocaine (1.5 mg/kg), and the other received IV morphine (0.1 mg/kg). Pain scores and adverse effects were assessed at 15, 30, 45 and 60 minutes and patients’ satisfaction was evaluated two hours later. A minimum pain score reduction of 1.3 from baseline was considered clinically significant. Results: Fifty patients with the mean age of 31.28 ± 8.7 were enrolled (78% male). The demographic characteristics and pain scores of the two groups was similar. The on-arrival mean pain scores in two groups were, lidocaine: 7.9 ± 1.4 and morphine: 8.0 ± 1.4 (p = 0.57) and after 1 hour were, lidocaine: 2.28 ± 1.2 and morphine: 3.2 ± 1.7. Although the pain score decreased significantly in both group (p = 0.027), there were not any clinically and statistically significant difference between the two groups (p = 0.77). Patients’ satisfaction with pain management in both groups were almost similar (p = 0.49). Conclusion: The reduction in pain score using IV lidocaine is not superior to IV morphine in adult ED patients with traumatic limb pain.
AB - Introduction: This study was designed to assess the possible superiority of intravenous lidocaine to morphine for pain management. Methods: This was a randomized double blind controlled superiority trial, carried on in the emergency department (ED). Traumatic patients older than 18-year-old with the complaint of acute pain greater than 4 on a numeric rating scale (NRS) from 0 to 10 on their extremities were eligible. One group received IV lidocaine (1.5 mg/kg), and the other received IV morphine (0.1 mg/kg). Pain scores and adverse effects were assessed at 15, 30, 45 and 60 minutes and patients’ satisfaction was evaluated two hours later. A minimum pain score reduction of 1.3 from baseline was considered clinically significant. Results: Fifty patients with the mean age of 31.28 ± 8.7 were enrolled (78% male). The demographic characteristics and pain scores of the two groups was similar. The on-arrival mean pain scores in two groups were, lidocaine: 7.9 ± 1.4 and morphine: 8.0 ± 1.4 (p = 0.57) and after 1 hour were, lidocaine: 2.28 ± 1.2 and morphine: 3.2 ± 1.7. Although the pain score decreased significantly in both group (p = 0.027), there were not any clinically and statistically significant difference between the two groups (p = 0.77). Patients’ satisfaction with pain management in both groups were almost similar (p = 0.49). Conclusion: The reduction in pain score using IV lidocaine is not superior to IV morphine in adult ED patients with traumatic limb pain.
KW - Acute pain
KW - Emergency service, hospital
KW - Lidocaine
KW - Morphine
KW - Pain management
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U2 - 10.1016/j.ajem.2017.12.027
DO - 10.1016/j.ajem.2017.12.027
M3 - Article
C2 - 29254669
AN - SCOPUS:85039432995
SN - 0735-6757
VL - 36
SP - 1231
EP - 1235
JO - American Journal of Emergency Medicine
JF - American Journal of Emergency Medicine
IS - 7
ER -