Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation

Keyphrases

• Oxysterols 100%
• Cholesterol Synthesis 100%
• Inflammasome Activation 100%
• Absent in Melanoma 2 (AIM2) 100%
• Macrophages 66%
• CH25H 66%
• Interleukin-1β 50%
• Cholesterol 33%
• Activated Macrophages 33%
• Mitochondrial DNA 33%
• 25-hydroxycholesterol 33%
• Inflammation 16%
• Transcription Factor 16%
• Cholesterol Levels 16%
• Lipid Metabolism 16%
• Sterol Regulatory Element-binding protein-1c (SREBP-1c) 16%
• Sensor Protein 16%
• Bacterial Infection 16%
• Hydroxylase Deficiency 16%
• Bacterial Lipopolysaccharide 16%
• Molecular Link 16%
• Type I Interferon 16%
• DNA Biosensor 16%
• SREBP2 16%
• Mitochondrial Integrity 16%
• Inflammasome 16%
• Lipopolysaccharide Stimulation 16%
• Mitochondrial Respiratory Function 16%
• DNA Release 16%

Biochemistry, Genetics and Molecular Biology

• Macrophage 100%
• Oxysterol 100%
• Cholesterol Synthesis 100%
• Inflammasome 100%
• Oxygenase 66%
• Interleukin-1 50%
• Mitochondrial DNA 33%
• Transcription Factors 16%
• Lipid Metabolism 16%
• interferon 16%
• Sterol Regulatory Element-Binding Protein 16%
• Lipopolysaccharide 16%
• Sterol Regulatory Element Binding Protein 2 16%

Immunology and Microbiology

• Macrophage 100%
• Cholesterol Synthesis 100%
• Inflammasome 100%
• Interleukin 1 50%
• interferon 16%
• Transcription Factors 16%
• Sterol Regulatory Element Binding Protein 16%
• Cytosol 16%
• Lipid Metabolism 16%
• Sterol Regulatory Element Binding Protein 2 16%