Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms

Patricio M. Polanco; Ying Ding; Jordan M. Knox; Lekshmi Ramalingam; Heather Jones; Melissa E. Hogg; Amer H. Zureikat; Matthew P. Holtzman; James Pingpank; Steven Ahrendt; Herbert J. Zeh; David L. Bartlett; Haroon A. Choudry

doi:10.1245/s10434-015-4838-z

Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms

Patricio M. Polanco, Ying Ding, Jordan M. Knox, Lekshmi Ramalingam, Heather Jones, Melissa E. Hogg, Amer H. Zureikat, Matthew P. Holtzman, James Pingpank, Steven Ahrendt, Herbert J. Zeh, David L. Bartlett, Haroon A. Choudry

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21 Scopus citations

Abstract

Background: High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG–HV) peritoneal metastases in whom the utility of this aggressive approach is controversial. Methods: Prospectively collected perioperative data were compared between patients with peritoneal metastases from HG–HV MAN, defined as simplified peritoneal cancer index (SPCI) ≥12, and those with high-grade, low-volume (HG–LV; SPCI

Original language	English (US)
Pages (from-to)	382-390
Number of pages	9
Journal	Annals of Surgical Oncology
Volume	23
Issue number	2
DOIs	https://doi.org/10.1245/s10434-015-4838-z
State	Published - Feb 1 2016

ASJC Scopus subject areas

Surgery
Oncology

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Polanco, P. M., Ding, Y., Knox, J. M., Ramalingam, L., Jones, H., Hogg, M. E., Zureikat, A. H., Holtzman, M. P., Pingpank, J., Ahrendt, S., Zeh, H. J., Bartlett, D. L., & Choudry, H. A. (2016). Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms. Annals of Surgical Oncology, 23(2), 382-390. https://doi.org/10.1245/s10434-015-4838-z

Polanco, PM, Ding, Y, Knox, JM, Ramalingam, L, Jones, H, Hogg, ME, Zureikat, AH, Holtzman, MP, Pingpank, J, Ahrendt, S, Zeh, HJ, Bartlett, DL & Choudry, HA 2016, 'Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms', Annals of Surgical Oncology, vol. 23, no. 2, pp. 382-390. https://doi.org/10.1245/s10434-015-4838-z

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title = "Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms",

abstract = "Background: High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG–HV) peritoneal metastases in whom the utility of this aggressive approach is controversial. Methods: Prospectively collected perioperative data were compared between patients with peritoneal metastases from HG–HV MAN, defined as simplified peritoneal cancer index (SPCI) ≥12, and those with high-grade, low-volume (HG–LV; SPCI ",

author = "Polanco, {Patricio M.} and Ying Ding and Knox, {Jordan M.} and Lekshmi Ramalingam and Heather Jones and Hogg, {Melissa E.} and Zureikat, {Amer H.} and Holtzman, {Matthew P.} and James Pingpank and Steven Ahrendt and Zeh, {Herbert J.} and Bartlett, {David L.} and Choudry, {Haroon A.}",

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doi = "10.1245/s10434-015-4838-z",

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T1 - Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms

AU - Polanco, Patricio M.

AU - Ding, Ying

AU - Knox, Jordan M.

AU - Ramalingam, Lekshmi

AU - Jones, Heather

AU - Hogg, Melissa E.

AU - Zureikat, Amer H.

AU - Holtzman, Matthew P.

AU - Pingpank, James

AU - Ahrendt, Steven

AU - Zeh, Herbert J.

AU - Bartlett, David L.

AU - Choudry, Haroon A.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Background: High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG–HV) peritoneal metastases in whom the utility of this aggressive approach is controversial. Methods: Prospectively collected perioperative data were compared between patients with peritoneal metastases from HG–HV MAN, defined as simplified peritoneal cancer index (SPCI) ≥12, and those with high-grade, low-volume (HG–LV; SPCI

AB - Background: High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG–HV) peritoneal metastases in whom the utility of this aggressive approach is controversial. Methods: Prospectively collected perioperative data were compared between patients with peritoneal metastases from HG–HV MAN, defined as simplified peritoneal cancer index (SPCI) ≥12, and those with high-grade, low-volume (HG–LV; SPCI

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Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms

Abstract

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