Ototoxicity of topical agents

G. N. Rohn, W. L. Meyerhoff, C. G. Wright

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Topical otic preparations are commonly prescribed by otolaryngologists- head and neck surgeons. It is well documented in the literature that some agents in these preparations are ototoxic when applied to the middle ear in experimental animals, although the occurrence of ototoxicity in the clinical setting is controversial. This article discusses topical otic preparations currently available as well as various other agents. The clinician should prescribe these preparations with close surveillance for potential ototoxicity.

Original languageEnglish (US)
Pages (from-to)747-758
Number of pages12
JournalOtolaryngologic Clinics of North America
Issue number5
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Otorhinolaryngology


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