Abstract
Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a “double duty” in this cascade transformation, which proceeds through an SN2’-substitution followed by a consequent cycloisomerization step.
Original language | English (US) |
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Pages (from-to) | 1516-1526 |
Number of pages | 11 |
Journal | Chemistry of Heterocyclic Compounds |
Volume | 47 |
Issue number | 12 |
State | Published - Mar 1 2012 |
Externally published | Yes |
Keywords
- Allenes
- Cycloisomerization
- Indolizines
- Propargyl mesylates
- Synthetic methods
ASJC Scopus subject areas
- Organic Chemistry