Abstract
Introduction: Capsular warning syndrome (CWS) carries a significant risk of permanent stroke. There are no proven therapies for preventing completed stroke in this unstable situation. Methods: Clinical observation in two patients with aspirin-resistant CWS treated with a loading dose of oral clopidogrel. Results: Both patients had excellent neurological outcome, although one sustained an asymptomatic brain infarction. Conclusion: High-dose oral clopidogrel plus aspirin merits formal evaluation in high-risk transient brain ischemia such as CWS, preferably in a randomized trial compared to aspirin alone.
Original language | English (US) |
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Pages (from-to) | 183-184 |
Number of pages | 2 |
Journal | Neurocritical Care |
Volume | 2 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2005 |
Keywords
- Acute brain ischemia
- Antiplatelet therapy
- Capsular warning syndrome
- Ischemic stroke
- Transient ischemic attack
ASJC Scopus subject areas
- Clinical Neurology
- Critical Care and Intensive Care Medicine