Optical pharmacokinetics to assess the permeability of angiogenic neovasculature

Irving J. Bigio, Judith R. Mourant, Gerrit Los, Robert F. Mattrey

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The method of Optical Pharmacokinetics is used for noninvasive measurement of drug concentrations in tissue. A rapid sequence of such measurements, following administration of a short bolus of appropriate optical contrast agent, can be used to assess the permeability of neovasculature, hence angiogenesis.

Original languageEnglish (US)
Title of host publicationBiomedical Topical Meeting, BIOMED 2002
PublisherOptica Publishing Group (formerly OSA)
Number of pages3
ISBN (Electronic)1557527024
StatePublished - 2002
Externally publishedYes
EventBiomedical Topical Meeting, BIOMED 2002 - Miami Beach, United States
Duration: Apr 7 2002Apr 10 2002

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceBiomedical Topical Meeting, BIOMED 2002
Country/TerritoryUnited States
CityMiami Beach

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials


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