Optical Imaging of Intrinsic Signals

N. Pouratian; S. Sheth

doi:10.1016/B978-008045046-9.00316-8

Optical Imaging of Intrinsic Signals

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Optical imaging of intrinsic signals maps the brain by measuring intrinsic activity-related changes in tissue light reflectance and absorbance. These signals result from changes in local blood volume, hemoglobin oxygenation, and tissue light scattering changes that are coupled to neuronal activity. Because it offers an excellent combination of spatial sampling, spatial resolution, and temporal resolution, it is a versatile brain mapping tool that can be used alone or in combination with other brain mapping techniques to characterize neurovascular physiology, map the brain, and investigate disease in a variety of species, including rodents, primates, and humans.

Original language	English (US)
Title of host publication	Encyclopedia of Neuroscience
Publisher	Elsevier Ltd
Pages	271-278
Number of pages	8
ISBN (Print)	9780080450469
DOIs	https://doi.org/10.1016/B978-008045046-9.00316-8
State	Published - 2009
Externally published	Yes

Keywords

Brain
Brain mapping
Cerebral metabolism
Cortical mapping
Functional imaging
Imaging
Intrinsic signal imaging
Neurovascular coupling
Neurovascular physiology
Optical imaging

ASJC Scopus subject areas

General Neuroscience

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10.1016/B978-008045046-9.00316-8

Cite this

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title = "Optical Imaging of Intrinsic Signals",

abstract = "Optical imaging of intrinsic signals maps the brain by measuring intrinsic activity-related changes in tissue light reflectance and absorbance. These signals result from changes in local blood volume, hemoglobin oxygenation, and tissue light scattering changes that are coupled to neuronal activity. Because it offers an excellent combination of spatial sampling, spatial resolution, and temporal resolution, it is a versatile brain mapping tool that can be used alone or in combination with other brain mapping techniques to characterize neurovascular physiology, map the brain, and investigate disease in a variety of species, including rodents, primates, and humans.",

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AU - Sheth, S.

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AB - Optical imaging of intrinsic signals maps the brain by measuring intrinsic activity-related changes in tissue light reflectance and absorbance. These signals result from changes in local blood volume, hemoglobin oxygenation, and tissue light scattering changes that are coupled to neuronal activity. Because it offers an excellent combination of spatial sampling, spatial resolution, and temporal resolution, it is a versatile brain mapping tool that can be used alone or in combination with other brain mapping techniques to characterize neurovascular physiology, map the brain, and investigate disease in a variety of species, including rodents, primates, and humans.

KW - Brain

KW - Brain mapping

KW - Cerebral metabolism

KW - Cortical mapping

KW - Functional imaging

KW - Imaging

KW - Intrinsic signal imaging

KW - Neurovascular coupling

KW - Neurovascular physiology

KW - Optical imaging

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M3 - Chapter

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SN - 9780080450469

SP - 271

EP - 278

BT - Encyclopedia of Neuroscience

PB - Elsevier Ltd

ER -

Optical Imaging of Intrinsic Signals

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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