Nucleotide Excision Repair: Biology

E. C. Friedberg

doi:10.1016/B978-0-12-378630-2.00254-1

Nucleotide Excision Repair: Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Nucleotide excision repair (NER) is a fundamental DNA repair process that is ubiquitously distributed from bacteria to humans. The process is essential for the enzyme-catalyzed removal of various types of base damage from the nuclear genome, typically those that result in significant distortion of the helical structure of DNA. This article discusses the overview and biology of NER.

Original language	English (US)
Title of host publication	Encyclopedia of Biological Chemistry
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	337-340
Number of pages	4
ISBN (Electronic)	9780123786319
ISBN (Print)	9780123786302
DOIs	https://doi.org/10.1016/B978-0-12-378630-2.00254-1
State	Published - Feb 15 2013

Keywords

Human disease
Nucleotide excision repair
Pyrimidine dimmers
UV radiation
Xeroderma pigmentosum

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/B978-0-12-378630-2.00254-1

Cite this

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abstract = "Nucleotide excision repair (NER) is a fundamental DNA repair process that is ubiquitously distributed from bacteria to humans. The process is essential for the enzyme-catalyzed removal of various types of base damage from the nuclear genome, typically those that result in significant distortion of the helical structure of DNA. This article discusses the overview and biology of NER.",

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AB - Nucleotide excision repair (NER) is a fundamental DNA repair process that is ubiquitously distributed from bacteria to humans. The process is essential for the enzyme-catalyzed removal of various types of base damage from the nuclear genome, typically those that result in significant distortion of the helical structure of DNA. This article discusses the overview and biology of NER.

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KW - Pyrimidine dimmers

KW - UV radiation

KW - Xeroderma pigmentosum

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BT - Encyclopedia of Biological Chemistry

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ER -

Nucleotide Excision Repair: Biology

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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