NR Supplementation During Lactation: Benefiting Mother and Child

Dengbao Yang; Yihong Wan

doi:10.1016/j.tem.2019.02.004

NR Supplementation During Lactation: Benefiting Mother and Child

Dengbao Yang, Yihong Wan

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Abnormal nicotinamide adenine dinucleotide (NAD ⁺ ) metabolism causes a wide spectrum of diseases. A recent study (Cell Rep. 2019;26:969–983) shows that postpartum NAD ⁺ homeostasis is depressed. By restoring NAD ⁺ homeostasis, maternal nicotinamide riboside (NR) supplementation during lactation enhances postpartum weight loss, as well as juvenile development and adult neurogenesis in the offspring.

Original language	English (US)
Pages (from-to)	225-227
Number of pages	3
Journal	Trends in Endocrinology and Metabolism
Volume	30
Issue number	4
DOIs	https://doi.org/10.1016/j.tem.2019.02.004
State	Published - Apr 2019

Keywords

NAD metabolism
neurogenesis
nicotinamide riboside
offspring development
postpartum
weight loss

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.tem.2019.02.004

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title = "NR Supplementation During Lactation: Benefiting Mother and Child",

abstract = " Abnormal nicotinamide adenine dinucleotide (NAD + ) metabolism causes a wide spectrum of diseases. A recent study (Cell Rep. 2019;26:969–983) shows that postpartum NAD + homeostasis is depressed. By restoring NAD + homeostasis, maternal nicotinamide riboside (NR) supplementation during lactation enhances postpartum weight loss, as well as juvenile development and adult neurogenesis in the offspring.",

keywords = "NAD metabolism, neurogenesis, nicotinamide riboside, offspring development, postpartum, weight loss",

author = "Dengbao Yang and Yihong Wan",

note = "Funding Information: Y.W. is Lawrence Raisz Professor in Bone Cell Metabolism and a Virginia Murchison Linthicum Scholar in Medical Research. This work was in part supported by The Welch Foundation (I-1751, Y.W.), NIH (R01CA229487, R01CA236802, Y.W.), CPRIT (RP180047, Y.W.), DOD (W81XWH-18-1-0014, Y.W.) and UTSW Endowed Scholar Startup Fund (Y.W.). The authors declare that they have no financial conflict of interest. Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = apr,

doi = "10.1016/j.tem.2019.02.004",

language = "English (US)",

volume = "30",

pages = "225--227",

journal = "Trends in Endocrinology and Metabolism",

issn = "1043-2760",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - NR Supplementation During Lactation

T2 - Benefiting Mother and Child

AU - Yang, Dengbao

AU - Wan, Yihong

N1 - Funding Information: Y.W. is Lawrence Raisz Professor in Bone Cell Metabolism and a Virginia Murchison Linthicum Scholar in Medical Research. This work was in part supported by The Welch Foundation (I-1751, Y.W.), NIH (R01CA229487, R01CA236802, Y.W.), CPRIT (RP180047, Y.W.), DOD (W81XWH-18-1-0014, Y.W.) and UTSW Endowed Scholar Startup Fund (Y.W.). The authors declare that they have no financial conflict of interest. Publisher Copyright: © 2019 Elsevier Ltd

PY - 2019/4

Y1 - 2019/4

N2 - Abnormal nicotinamide adenine dinucleotide (NAD + ) metabolism causes a wide spectrum of diseases. A recent study (Cell Rep. 2019;26:969–983) shows that postpartum NAD + homeostasis is depressed. By restoring NAD + homeostasis, maternal nicotinamide riboside (NR) supplementation during lactation enhances postpartum weight loss, as well as juvenile development and adult neurogenesis in the offspring.

AB - Abnormal nicotinamide adenine dinucleotide (NAD + ) metabolism causes a wide spectrum of diseases. A recent study (Cell Rep. 2019;26:969–983) shows that postpartum NAD + homeostasis is depressed. By restoring NAD + homeostasis, maternal nicotinamide riboside (NR) supplementation during lactation enhances postpartum weight loss, as well as juvenile development and adult neurogenesis in the offspring.

KW - NAD metabolism

KW - neurogenesis

KW - nicotinamide riboside

KW - offspring development

KW - postpartum

KW - weight loss

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U2 - 10.1016/j.tem.2019.02.004

DO - 10.1016/j.tem.2019.02.004

M3 - Short survey

C2 - 30797625

AN - SCOPUS:85061751153

SN - 1043-2760

VL - 30

SP - 225

EP - 227

JO - Trends in Endocrinology and Metabolism

JF - Trends in Endocrinology and Metabolism

IS - 4

ER -

NR Supplementation During Lactation: Benefiting Mother and Child

Abstract

Keywords

ASJC Scopus subject areas

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