Nosocomial infection in the NICU: A medical complication or unavoidable problem?

Reese Clark, Richard Powers, Robert White, Barry Bloom, Pablo Sanchez, Daniel K. Benjamin

Research output: Contribution to journalReview articlepeer-review

81 Scopus citations


Nosocomial sepsis is a serious problem for neonates who are admitted for intensive care. As it is associated with increases in mortality, morbidity, and prolonged length of hospital stay, both the human and fiscal costs of these infections are high. Although the rate of nosocomial sepsis increases with the degree of both prematurity and low birth weight, no specific lab test has been shown to be very useful in improving our ability to predict who has a "real" blood-stream infection and, therefore, who needs to be treated with a full course of antibiotics. As a result, antibiotic use is double the rate of " proven" sepsis and we are facilitating the growth of resistant organisms in the neonatal intensive care unit. The purpose of this article is to review the topic of nosocomial infections in neonates.

Original languageEnglish (US)
Pages (from-to)382-388
Number of pages7
JournalJournal of Perinatology
Issue number6
StatePublished - Jun 2004

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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