Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off-resonance and flow

Peng Hu; Christian T. Stoeck; Jouke Smink; Dana C. Peters; Long Ngo; Beth Goddu; Kraig V. Kissinger; Lois A. Goepfert; Jonathan Chan; Thomas H. Hauser; Neil M. Rofsky; Warren J. Manning; Reza Nezafat

doi:10.1002/jmri.22356

Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off-resonance and flow

Peng Hu, Christian T. Stoeck, Jouke Smink, Dana C. Peters, Long Ngo, Beth Goddu, Kraig V. Kissinger, Lois A. Goepfert, Jonathan Chan, Thomas H. Hauser, Neil M. Rofsky, Warren J. Manning, Reza Nezafat

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Purpose To investigate pulmonary vein (PV) off-resonance and blood flow as causes of signal void artifacts in noncontrast steady-state-free-precession (SSFP) PV magnetic resonance angiography (MRA). Materials and Methods PV blood off-resonance was measured on 11 healthy adult subjects and 10 atrial fibrillation (AF) patients. Noncontrast PV MRA was performed using a 3D slab-selective SSFP sequence at 1.5T on seven healthy subjects with signal profile shifts of 0-125 Hz. The time-resolved blood flow velocity of the PVs was measured on five healthy subjects. The impact of flow was studied on six healthy subjects, on whom SSFP PV MRA was acquired twice with the electrocardiogram (ECG) trigger delay corresponding to low and high flow, respectively. Results The PV off-resonances were 97 ± 27 Hz, 65 ± 20 Hz, 74 ± 25 Hz, and 52 ± 17 Hz for right inferior, left inferior, right superior, and left superior PVs, respectively, on healthy subjects, and 74 ± 20 Hz, 38 ± 9 Hz, 51 ± 20 Hz, and 28 ± 11 Hz on AF patients (P<0.01 for all). The off-resonance caused severe signal voids in the PVs. Signal acquired during mid-diastole with high PV flow caused additional signal voids in the left atrium, which was reduced by setting the ECG trigger delay to late-diastole. Conclusion PV off-resonance and flow causes signal void artifacts in noncontrast 3D slab-selective SSFP PV MRA.

Original language	English (US)
Pages (from-to)	1255-1261
Number of pages	7
Journal	Journal of Magnetic Resonance Imaging
Volume	32
Issue number	5
DOIs	https://doi.org/10.1002/jmri.22356
State	Published - Nov 2010

Keywords

SSFP
atrial fibrillation
noncontrast
off-resonance
pulmonary vein angiography

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/jmri.22356

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Hu, P., Stoeck, C. T., Smink, J., Peters, D. C., Ngo, L., Goddu, B., Kissinger, K. V., Goepfert, L. A., Chan, J., Hauser, T. H., Rofsky, N. M., Manning, W. J., & Nezafat, R. (2010). Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off-resonance and flow. Journal of Magnetic Resonance Imaging, 32(5), 1255-1261. https://doi.org/10.1002/jmri.22356

@article{0f19bcfedb004c9cafa19e00d8b1fa6e,

title = "Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off-resonance and flow",

abstract = "Purpose To investigate pulmonary vein (PV) off-resonance and blood flow as causes of signal void artifacts in noncontrast steady-state-free-precession (SSFP) PV magnetic resonance angiography (MRA). Materials and Methods PV blood off-resonance was measured on 11 healthy adult subjects and 10 atrial fibrillation (AF) patients. Noncontrast PV MRA was performed using a 3D slab-selective SSFP sequence at 1.5T on seven healthy subjects with signal profile shifts of 0-125 Hz. The time-resolved blood flow velocity of the PVs was measured on five healthy subjects. The impact of flow was studied on six healthy subjects, on whom SSFP PV MRA was acquired twice with the electrocardiogram (ECG) trigger delay corresponding to low and high flow, respectively. Results The PV off-resonances were 97 ± 27 Hz, 65 ± 20 Hz, 74 ± 25 Hz, and 52 ± 17 Hz for right inferior, left inferior, right superior, and left superior PVs, respectively, on healthy subjects, and 74 ± 20 Hz, 38 ± 9 Hz, 51 ± 20 Hz, and 28 ± 11 Hz on AF patients (P<0.01 for all). The off-resonance caused severe signal voids in the PVs. Signal acquired during mid-diastole with high PV flow caused additional signal voids in the left atrium, which was reduced by setting the ECG trigger delay to late-diastole. Conclusion PV off-resonance and flow causes signal void artifacts in noncontrast 3D slab-selective SSFP PV MRA.",

keywords = "SSFP, atrial fibrillation, noncontrast, off-resonance, pulmonary vein angiography",

author = "Peng Hu and Stoeck, {Christian T.} and Jouke Smink and Peters, {Dana C.} and Long Ngo and Beth Goddu and Kissinger, {Kraig V.} and Goepfert, {Lois A.} and Jonathan Chan and Hauser, {Thomas H.} and Rofsky, {Neil M.} and Manning, {Warren J.} and Reza Nezafat",

year = "2010",

month = nov,

doi = "10.1002/jmri.22356",

language = "English (US)",

volume = "32",

pages = "1255--1261",

journal = "Journal of Magnetic Resonance Imaging",

issn = "1053-1807",

publisher = "John Wiley and Sons Inc.",

number = "5",

}

TY - JOUR

T1 - Noncontrast SSFP pulmonary vein magnetic resonance angiography

T2 - Impact of off-resonance and flow

AU - Hu, Peng

AU - Stoeck, Christian T.

AU - Smink, Jouke

AU - Peters, Dana C.

AU - Ngo, Long

AU - Goddu, Beth

AU - Kissinger, Kraig V.

AU - Goepfert, Lois A.

AU - Chan, Jonathan

AU - Hauser, Thomas H.

AU - Rofsky, Neil M.

AU - Manning, Warren J.

AU - Nezafat, Reza

PY - 2010/11

Y1 - 2010/11

N2 - Purpose To investigate pulmonary vein (PV) off-resonance and blood flow as causes of signal void artifacts in noncontrast steady-state-free-precession (SSFP) PV magnetic resonance angiography (MRA). Materials and Methods PV blood off-resonance was measured on 11 healthy adult subjects and 10 atrial fibrillation (AF) patients. Noncontrast PV MRA was performed using a 3D slab-selective SSFP sequence at 1.5T on seven healthy subjects with signal profile shifts of 0-125 Hz. The time-resolved blood flow velocity of the PVs was measured on five healthy subjects. The impact of flow was studied on six healthy subjects, on whom SSFP PV MRA was acquired twice with the electrocardiogram (ECG) trigger delay corresponding to low and high flow, respectively. Results The PV off-resonances were 97 ± 27 Hz, 65 ± 20 Hz, 74 ± 25 Hz, and 52 ± 17 Hz for right inferior, left inferior, right superior, and left superior PVs, respectively, on healthy subjects, and 74 ± 20 Hz, 38 ± 9 Hz, 51 ± 20 Hz, and 28 ± 11 Hz on AF patients (P<0.01 for all). The off-resonance caused severe signal voids in the PVs. Signal acquired during mid-diastole with high PV flow caused additional signal voids in the left atrium, which was reduced by setting the ECG trigger delay to late-diastole. Conclusion PV off-resonance and flow causes signal void artifacts in noncontrast 3D slab-selective SSFP PV MRA.

AB - Purpose To investigate pulmonary vein (PV) off-resonance and blood flow as causes of signal void artifacts in noncontrast steady-state-free-precession (SSFP) PV magnetic resonance angiography (MRA). Materials and Methods PV blood off-resonance was measured on 11 healthy adult subjects and 10 atrial fibrillation (AF) patients. Noncontrast PV MRA was performed using a 3D slab-selective SSFP sequence at 1.5T on seven healthy subjects with signal profile shifts of 0-125 Hz. The time-resolved blood flow velocity of the PVs was measured on five healthy subjects. The impact of flow was studied on six healthy subjects, on whom SSFP PV MRA was acquired twice with the electrocardiogram (ECG) trigger delay corresponding to low and high flow, respectively. Results The PV off-resonances were 97 ± 27 Hz, 65 ± 20 Hz, 74 ± 25 Hz, and 52 ± 17 Hz for right inferior, left inferior, right superior, and left superior PVs, respectively, on healthy subjects, and 74 ± 20 Hz, 38 ± 9 Hz, 51 ± 20 Hz, and 28 ± 11 Hz on AF patients (P<0.01 for all). The off-resonance caused severe signal voids in the PVs. Signal acquired during mid-diastole with high PV flow caused additional signal voids in the left atrium, which was reduced by setting the ECG trigger delay to late-diastole. Conclusion PV off-resonance and flow causes signal void artifacts in noncontrast 3D slab-selective SSFP PV MRA.

KW - SSFP

KW - atrial fibrillation

KW - noncontrast

KW - off-resonance

KW - pulmonary vein angiography

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U2 - 10.1002/jmri.22356

DO - 10.1002/jmri.22356

M3 - Article

C2 - 21031533

AN - SCOPUS:78349290083

SN - 1053-1807

VL - 32

SP - 1255

EP - 1261

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

IS - 5

ER -

Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off-resonance and flow

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Keywords

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