TY - JOUR
T1 - New perspectives on brain death
AU - Kirschen, Matthew P.
AU - Lewis, Ariane
AU - Rubin, Michael
AU - Kurtz, Pedro
AU - Greer, David M.
N1 - Publisher Copyright:
©
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Brain death, or death by neurological criteria (BD/DNC), has been accepted conceptually, medically and legally for decades. Nevertheless, some areas remain controversial or understudied, pointing to a need for focused research to advance the field. Multiple recent contributions have increased our understanding of BD/DNC, solidified our practice and provided guidance where previously lacking. There have also been important developments on a global scale, including in low-to-middle income countries such as in South America. Although variability in protocols and practice still exists, new efforts are underway to reduce inconsistencies and better train practitioners in accurate and sound BD/DNC determination. Various legal challenges have required formal responses from national societies, and the American Academy of Neurology has filled this void with much needed guidance. Questions remain regarding concepts such as € whole brain' versus € brainstem' death, and the intersection of BD/DNC and rubrics of medical futility. These concepts are the subject of this review.
AB - Brain death, or death by neurological criteria (BD/DNC), has been accepted conceptually, medically and legally for decades. Nevertheless, some areas remain controversial or understudied, pointing to a need for focused research to advance the field. Multiple recent contributions have increased our understanding of BD/DNC, solidified our practice and provided guidance where previously lacking. There have also been important developments on a global scale, including in low-to-middle income countries such as in South America. Although variability in protocols and practice still exists, new efforts are underway to reduce inconsistencies and better train practitioners in accurate and sound BD/DNC determination. Various legal challenges have required formal responses from national societies, and the American Academy of Neurology has filled this void with much needed guidance. Questions remain regarding concepts such as € whole brain' versus € brainstem' death, and the intersection of BD/DNC and rubrics of medical futility. These concepts are the subject of this review.
KW - acquired brain injury
KW - traumatic brain injury
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U2 - 10.1136/jnnp-2020-323952
DO - 10.1136/jnnp-2020-323952
M3 - Review article
C2 - 33219040
AN - SCOPUS:85102152987
SN - 0022-3050
VL - 92
SP - 255
EP - 262
JO - Journal of Neurology, Neurosurgery and psychiatry
JF - Journal of Neurology, Neurosurgery and psychiatry
IS - 3
ER -