Abstract
Background: Non-small-cell carcinoma of the lung has long been considered a chemotherapeutically resistant neoplasm. Newer agents and combinations are being tested. Methods: The authors have reviewed data on recent and active phase I and phase II trials of several new agents and combinations. Results: New drugs that affect both response rates and survival include vinorelbine, paclitaxel, docetaxel, gemcitabine, topotecan, and irinotecan. Conclusions: The advent of several relatively well-tolerated agents that alone have beneficial effects in advanced non-small-cell lung cancer provides reasonable hope that more effective drug combinations will soon be available for this disease.
Original language | English (US) |
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Pages (from-to) | 317-325 |
Number of pages | 9 |
Journal | Cancer Control |
Volume | 4 |
Issue number | 4 |
DOIs | |
State | Published - 1997 |
ASJC Scopus subject areas
- Hematology
- Oncology