Neurosyphilis masquerading as corticobasal degeneration

Julián Benito-León, J. Alvarez-Linera, E. D. Louis

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


We report on a patient with a syndrome resembling corticobasal ganglionic degeneration (CBD), including slight cognitive impairment, asymmetric akinesia, rigidity with myoclonus, and arm levitation, which can be one of the features of alien limb phenomenon; however, further diagnostic testing was consistent with neurosyphilis. Syphilis, "the great imitator," may also masquerade as CBD. Because neurosyphilis is treatable, it should be considered in the workup of patients with cognitive impairment and motor signs of CBD.

Original languageEnglish (US)
Pages (from-to)1367-1370
Number of pages4
JournalMovement Disorders
Issue number11
StatePublished - Nov 2004
Externally publishedYes


  • Corticobasal degeneration
  • General paresis
  • MRI
  • Neurosyphilis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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