Neurologic Sequelae after Ingestion of Mussels Contaminated with Domoic Acid

S. Robert Snodgrass, F. S.S. Leijten, A. W. de Weerd, Trish M. Perl, James C. Hockin, Tom Kosatsky, Ewan C.d. Todd, Lucie Bédard, Robert S. Remis, Jeanne Teitelbaum, Stirling Carpenter, Neil R. Cashman

Research output: Contribution to journalLetterpeer-review

3 Scopus citations


To the Editor: The papers of Perl et al. and Teitelbaum et al. (June 21 issue)1,2 suggest the existence of a new and avoidable human excitotoxic syndrome and imply that others may be found. Perl et al. showed that the mussels in question produced domoic acid. However, the existence of a specific domoate-caused neuropathologic entity has not been proved, nor was a link established between dose and consequences. Many people apparently ate these mussels without harm. It is not the elderly who consume the greatest quantities of seafood. Many young people eat mussels in larger quantities and may be more…

Original languageEnglish (US)
Pages (from-to)1631-1633
Number of pages3
JournalNew England Journal of Medicine
Issue number23
StatePublished - Dec 6 1990

ASJC Scopus subject areas

  • General Medicine


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