Neurobehavioral and neurodiagnostic aspects of late-onset psychosis

C. Munro Cullum, Robert K. Heaton, M. Jackuelyn Harris, Dilip V. Jeste

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


The onset of psychotic symptoms later in life requires careful multidisciplinary evaluation, yet may pose significant diagnostic difficulties given current classification schema. Here we describe a patient with new onset of schizophrenia-like symptoms at age 61. Cognitive screening and laboratory tests were within normal limits. However, detailed neuropsychological studies suggested mild to moderate, diffuse cerebral dysfunction, and MR revealed an arachnoid cyst around the right sylvian fissure. Three annual follow-up evaluations demonstrated no additional cognitive deterioration. Neuropsychological findings are discussed along with limitations of current psychiatric nosology and cognitive screening tasks in older patients with new-onset psychosis.

Original languageEnglish (US)
Pages (from-to)371-382
Number of pages12
JournalArchives of Clinical Neuropsychology
Issue number5
StatePublished - 1994

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Psychiatry and Mental health


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