Nanoparticles in medicine: Therapeutic applications and developments

L. Zhang, F. X. Gu, J. M. Chan, A. Z. Wang, R. S. Langer, O. C. Farokhzad

Research output: Contribution to journalReview articlepeer-review

2164 Scopus citations

Abstract

Nanotechnology is the understanding and control of matter generally in the 1-100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. 1,2 Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents.

Original languageEnglish (US)
Pages (from-to)761-769
Number of pages9
JournalClinical pharmacology and therapeutics
Volume83
Issue number5
DOIs
StatePublished - May 30 2008
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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