N -acylsulfonamide assisted tandem C-H olefination/annulation: Synthesis of isoindolinones

Chen Zhu, J R Falck

Research output: Contribution to journalArticlepeer-review

148 Scopus citations


A tandem C-H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.(Figure Presented)

Original languageEnglish (US)
Pages (from-to)1214-1217
Number of pages4
JournalOrganic Letters
Issue number5
StatePublished - Mar 4 2011

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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