Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies

Shin J. Oh, Anjaneyulu Alapati, Gwen C. Claussen, Steven Vernino

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A young woman presented with facial myokymia in association with dermatomyositis. There was no evidence of peripheral neuropathy. Needle electromyography showed prominent myokymic discharges and brief neuromyotonic discharges in addition to many small-amplitude, shortduration motor unit potentials. Myokymia and dermatomyositis both responded to immunosuppressive treatment. The presence of antibodies to voltage-gated potassium channels and the association with dermatomyositis indicated an autoimmune cause for myokymia, which may have been due to reversible peripheral nerve hyperexcitability.

Original languageEnglish (US)
Pages (from-to)757-760
Number of pages4
JournalMuscle and Nerve
Issue number6
StatePublished - Jun 1 2003


  • Dermatomyositis
  • Isaacs' syndrome
  • Myokymia
  • Neuromyotonia
  • Voltage-gated K channel antibody

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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