Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: Signal amplification via multivalency

Medicine & Life Sciences

• 1,4,7-triazacyclononane-N,N',N''-triacetic acid 100%
• Gallium-68 98%
• Chelating Agents 64%
• Integrins 54%
• Positron-Emission Tomography 54%
• 1,4,7-triazacyclononane 36%
• Gallium 27%
• Molecular Probes 26%
• Severe Combined Immunodeficiency 24%
• Peptides 24%
• Radiopharmaceuticals 23%
• Molecular Imaging 22%
• Radio 19%
• Neoplasms 18%
• Inhibitory Concentration 50 17%
• Heterografts 17%
• High Pressure Liquid Chromatography 15%
• Acids 14%
• Temperature 13%
• Ligands 13%

Engineering & Materials Science

• Gallium 81%
• Positron emission tomography 80%
• Scaffolds 68%
• Amplification 58%
• Tumors 44%
• Imaging techniques 44%
• Peptides 38%
• Heterografts 26%
• Molecular imaging 25%
• Metabolites 19%
• Ligands 19%
• Acids 13%
• Temperature 5%

Chemical Compounds

• Positron 67%
• Chelating Agent 55%
• Probe 35%
• Radiopharmaceutical 11%
• Radiochemical Yield 11%
• Peptide 11%
• Kd 7%
• Metabolite 6%
• Ambient Reaction Temperature 5%
• Ligand 4%
• Acid 3%
• Application 3%