Multiplying messages LRRK beneath parkinson disease

William T. Dauer; Ming Guo

doi:10.1016/j.cell.2014.03.043

Multiplying messages LRRK beneath parkinson disease

Research output: Contribution to journal › Short survey › peer-review

Abstract

Parkinson Disease (PD) is a progressive neurodegenerative disorder with limited therapeutic options. In this issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of translational control, a pathogenic mechanism implicated in an increasing number of CNS neurodegenerative diseases, as well as in normal aging.

Original language	English (US)
Pages (from-to)	291-293
Number of pages	3
Journal	Cell
Volume	157
Issue number	2
DOIs	https://doi.org/10.1016/j.cell.2014.03.043
State	Published - Apr 10 2014
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2014.03.043

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title = "Multiplying messages LRRK beneath parkinson disease",

abstract = "Parkinson Disease (PD) is a progressive neurodegenerative disorder with limited therapeutic options. In this issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of translational control, a pathogenic mechanism implicated in an increasing number of CNS neurodegenerative diseases, as well as in normal aging.",

author = "Dauer, {William T.} and Ming Guo",

note = "Funding Information: We regret being unable to cite all relevant work because of space constrains. We thank Peter Todd for insightful discussions. Supported by the National Institute of Health (NIH) to W.T.D., and NIH, Ellison Medical Foundation and American Parkinson Disease Association to M.G.",

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AU - Dauer, William T.

AU - Guo, Ming

N1 - Funding Information: We regret being unable to cite all relevant work because of space constrains. We thank Peter Todd for insightful discussions. Supported by the National Institute of Health (NIH) to W.T.D., and NIH, Ellison Medical Foundation and American Parkinson Disease Association to M.G.

PY - 2014/4/10

Y1 - 2014/4/10

N2 - Parkinson Disease (PD) is a progressive neurodegenerative disorder with limited therapeutic options. In this issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of translational control, a pathogenic mechanism implicated in an increasing number of CNS neurodegenerative diseases, as well as in normal aging.

AB - Parkinson Disease (PD) is a progressive neurodegenerative disorder with limited therapeutic options. In this issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of translational control, a pathogenic mechanism implicated in an increasing number of CNS neurodegenerative diseases, as well as in normal aging.

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Multiplying messages LRRK beneath parkinson disease

Abstract

ASJC Scopus subject areas

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