Multinucleate cell angiohistiocytoma: A case report and review of the literature

Danielle S. Applebaum, Fareesa Shuja, Lindsey Hicks, Clay Cockerell, Sylvia Hsu

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Multinucleate cell angiohistiocytoma (MCAH) is a rare, benign vascular proliferation. Fewer than 80 cases have been reported to date, which may relate to under-recognition of this entity. Lesions are commonly asymptomatic and appear as erythematous to violaceous papules on the lower extremities and dorsal hands of middle-aged to elderly women. The characteristic histopathologic and immunohistochemical features of MCAH are essential for definitive diagnosis of MCAH. Multinucleate cell angiohistiocytoma follows a slowly progressive course, although spontaneous regression has been reported in rare cases. We present a case of MCAH to increase awareness and elucidate the characteristic clinical and histopathologic features of this disorder.

Original languageEnglish (US)
Article number4
JournalDermatology online journal
Issue number5
StatePublished - 2014

ASJC Scopus subject areas

  • Dermatology


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