Multicystic dysplastic kidney

April T. Bleich; Jodi S. Dashe

doi:10.1016/B978-0-323-44548-1.00015-2

Multicystic dysplastic kidney

April T. Bleich, Jodi S. Dashe

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

Original language	English (US)
Title of host publication	Obstetric Imaging
Subtitle of host publication	Fetal Diagnosis and Care, 2nd Edition
Publisher	Elsevier
Pages	58-62.e1
ISBN (Electronic)	9780323445481
DOIs	https://doi.org/10.1016/B978-0-323-44548-1.00015-2
State	Published - Jan 1 2017

Keywords

Compensatory hypertrophy
Corticomedullary differentiation
Renal dysplasia

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-323-44548-1.00015-2

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abstract = "Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.",

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N2 - Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

AB - Multicystic dysplastic kidney (MCDK) denotes a kidney in which the renal parenchyma is replaced by numerous smooth-walled cysts of varying size that do not communicate with a renal pelvis and are surrounded by echogenic cortex, with an atretic ureter. It is a form of severe dysplasia that typically results in a nonfunctioning kidney. It is bilateral in approximately 25% of cases, usually conferring a lethal prognosis. Unilateral MCDK is associated with contralateral renal anomalies in 30% to 40% of cases, most commonly vesicoureteral reflux or ureteropelvic junction obstruction. Nonrenal anomalies are also frequent, occurring in approximately 25% of cases, and the finding of an associated anomaly significantly increases the fetal aneuploidy risk.

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ER -

Multicystic dysplastic kidney

Abstract

Keywords

ASJC Scopus subject areas

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